Background and Aim: Fine Needle Aspiration Biopsy is an effective diagnostic method in the field of medical pathologies. Easiness, accuracy, validity and usefulness of this method have been verified frequently. This method is useful not only for soft tisse or even intraosseous lesions, but also recurrence of tumors (metastasis), resistence to treatment, verification of malignancy, differentiation between malignancy and benignment and determination of organisms causes infection. Unfortunately the use of this method is not common in dental pathology. So this study intendes to show the diagnostic value of FNA specially for intraosseous lesions causing jaw radiolucency.Methods and Materials: This investigation consisted of 80 patients who were referred to Taleghani General Hospital who were then referred to the pathology or surgery departments at Shahid Beheshti dental school.Cases consist of 29 females (36.25) % and 51 males (63.75%). Sampletaking was conducted using a 10 cc, gauge 19 syringe.Results: Results show 90% sensitivity and 75% specificity for jaw radiolucent lesions in FNA method. Correlation between FNA and jaw radiolucencies was significant (P<0.001) and it's power was at equal accepctable level according to cramer's V (phi - cramer's =0.623). Based on FNA cytology power, lesions with positive predictive value of 78.30 had a microscopic view compatible to the findings of other similar studies.Conclusion: FNA can be used as a reliable method for rapid, early and in expensive diagnosis, resulting in an on time, and appropriate treatment plan.

Background and Objectives: Breast cancer is the most common cancer among women worldwide. Fine needle aspiration biopsy (FNAB) is one of the methods of breast biopsy which is fast, easy and cost effective. The aim of this study was to evaluate the concordance rate between pathologic results of sonography or stereotaxy guided FNAB and guided core needle biopsy (CNB) in the evaluation of breast lesions.Materials & Methods: During December 2010 until March 2011, 36 female patients with 37 breast lesions referred to FNAB and CNB with the guide of sonography in 35 lesions and with the guide of stereotaxy in 2 lesions. The kappa statistic used to calculate the concordance coefficient.Results: The concordance rate between guided-FNAB and guided-CNB was 93% with using kappa coefficient. In 5 patients, subjected to breast surgery, malignancy was reported as well as in guided-FNAB or guided-CNB.Conclusion: Because of high concordance between these two techniques in the assessment of breast lesions, guided FNAB is recommended in the first step. Guided-CNB can be reserved for lesions with insufficient pathology results by guided-FNAB.

Fine needle aspiration biopsy (FNAB) is a safe, simple, and cost -effective method for the evaluation of palpable persistent (>3 wk.) lymphadenopathy. Differential diagnosis of persistent cervical lymphadenopathy is widely variable and include benign disorders & malignancies (primarye.g. Lymphomas & secondary including metastases). In a procedure evaluation study, we evaluated 61 cases of persistent lymphadenopathy referred to the Dr.Shariati s hospital in 2000 - 2001 in whom no cause for the lynphadenopathy could be found. We initially performed FNA and then open biopsy from the same lymph node. The specimens are evaluated for cytology and histopathology respectively by two pathologists in a double blind manner.Diagnosis was classified into three categories including: benign disorders, lymphomas, and metastatic carcinomas that in the FNAB group included 37.8%, 31.1%, 31.1% respectively and in the open biopsy group included 29.5%, 36.1%, 34.4% of patients respectively. In 55 patients the results of FNAB and open biopsy were similar. Out of the remainder, in 4 patients the result of FNAB was benign and of the open biopsy as lymphoma. In the other 2 patients the result of open biopsy showed metastatic carcinoma and of the FANB showed benign in one and Iymphomainanother. Sensitivity, specificity, positive and negative predictive values, and accuracy of FNAB in contrast to open biopsy for benign disorders are 100%, 88.4%, 78.3%, 100% and 91.8% respectively. The above values for lymphomas are 81.8%, 97.4%, 94.7%, 90.5% and 91.8% and for metastatic carcinoma are 90.5%, 100%, 100%, 95.2% and 96.7% respectively.In all above three diagnostic groups the results of FNAB in contrast to open biopsy are remarkable and it can replace open biopsy for diagnosis of many cases of persistent cervical lymphadenopathy.

Introduction. Opportunity to sperm in azospermic men is an essential component of successful intracytoplasmic sperm injection. This study evaluate the efficacy of fine needle biopsy (FNA) versus open biopsy for spermatozoid retrival in azospermic men. Methods. Fine needle biopsy was performed in 1030 azospermic men for sperm retrival. Testicular open biopsy was performed in any cases with no obtained sperm in FNA. About 50 percent of patients have normal FSH level and other ones have high FSH lenvel. Results. FNA had a success rate about 29 percent for sperm retrival in azospermic patients. In patients with FNA failure, open biopsy could retrieve sperm in 21 percent cases. FNA and open biopsy with each other could retrieve sperm in 44 percent of azospermic patients. Discussion. FNA may has a first role for sperm retrieval in azospermic patients, but use of open biopsy is necessary in patients with FNA failure.

Background: Transthoracic CT-guided percutaneous fine-needle aspiration biopsy (FNAB) has become a well- established diagnostic technique and been useful in differentiating malignant and benign pulmonary lesions.Materials and Methods: 505 patients (311 men and 194 women) aged 7-90 years old (mean age 56.2 years) with pulmonary lesions underwent CT-guided transthoracic fine-needle aspiration biopsy.Cytopathologic evaluation of FNAB samples was performed in all patients. In addition, each case was reviewed for complications, including pneumothorax and hemoptysis. Data were analysed using SPSS software for windows ver. 11.5.Results: FNAB samples were adequate for diagnosis in 410 (81.2%) of 505 patients. Two hundred and forty-nine lesions (60.7%0) were malignant, and 161 (39.3%) were benign or atypical. Thirty-four (6.7%) patients had pneumothorax out of which none of them required thoracostomy tube placement. Additionally, hemoptysis was noted in 9 (1.8%) patients and follow-up was carried out. No further complications were reported.Conclusion: CT-guided FNAB of pulmonary lesions can yield well-established diagnoses and it can be useful in the management of patients with suspected lung cancer.